Here comes the solution to GM MDI/MDI2 multiple interfaces cannot connect the device, the software doesn’t recognize the device problem.
Cannot connect to MDI problem usually can be solved by mdi firmware upgrade, check How to Update GM MDI & MDI2 Firmware?
If failed to update firmware and reported an error ‘MDI software is out of date’, you may have to format the SD card.
Remove MDI/MDI2 mainboard
Take out the SD card, format SD card
Try connecting MDI again, it should work without issue.